- Sebyne
- Sedniv
- Selydove
- Senchyne
- Shakhtars’k
- Shchastya
- Shchurove
- Shkarbinka
- Shlyakh
- Shtormove
- Shubranets
- Shyshkivtsi
- Silets’
- Sim”yane
- Sivers’k
- Skelka
- Skhidnytsya
- Slavs’ke
- Slobidka-Balinska
- Slov”yanka
- Slov”yans’ke
- Slyv”yanka
- Sobolivka
- Sofiivka
- Sofiyivka
- Sofiyivska Borschagivka
- Soldats’ke
- Staiky
- Stanytsya Luhans’ka
- Stara Yahilnytsia
- Starobil’s’k
- Starosoldatske
- Staryye Yarylovichi
- Stepanivka
- Stizhkivs’ke
- Storozhnytsya
- Studenok
- Sukhodil
- Sums’ke
- Surs’ko-Mykhaylivka
- Sverdlovsk
- Svetlodarsk
- Svitlodolyns’ke
- Svyatogorsk
- Synevyrska Poliana
- Syniukhyn Brid
